How to resolve the low grade inflammation of obesity
You can only store so much in a cupboard.
You will get to a point, where the cupboard is FULL TO CAPACITY. At this point in time,
you need a new cupboard or failing this, A BIGGER CUPBOARD. Now cupboards don’t change
size by themselves…………….. to get more cupboard space, you have to DO SOMETHING.
The same principle holds in the body. Your fat cells are storage cupboards. We all have
a set number of fat cell cupboards – some people, are blessed with a body with an enormous
number and others, well their body is not that well endowed. Cupboard space matters
– the more the merrier. The more cupboard space you have, the more fat you can safely
store. On paper at least, fat cells can expand their volume by 1000 times. When you exceed
YOUR fat storage capacity – metabolic troubles surface. But there is quite a bit of wiggle
room, built into the system. Because the fat storage cupboard, can be remodelled. Join
us for this episode of BETTER BODY CHEMISTRY TV, as we find out, what can go wrong with
fat cell remodelling. Better Body Chemistry TV is brought to you by Dr Sandy – a scientist
turned gremlin buster, HELPING YOU, battle sugar gremlins, heffa-lumps & other health
horribles, through BETTER BODY CHEMISTRY. Remember, small things can make a big difference
to your health. Fat cell remodelling is performed by the immune system. Surprised ? Don’t
be, the immune system is not just tasked with battling invading organisms, it is also does
repairs and remodelling. So, when your fat cells, need to expand, they call upon the
immune system for help. Macrophages rush in and do a little remodelling. They knock out
the “too small” foundation and replace it with a more spacious one and ensure that
the blood supply is re-routed, to keep expanded fat cell, adequately supplied with oxygen
and nutrients. When the job is done – they LEAVE. Well that is what is supposed to happen.
But it seems, this does not always happen. Instead of packing up their tools and going
“home”, they loiter. Their continued presecence, results in what is termed LOW GRADE INFLAMMATION.
It sparks a crisis. Because well let’s be honest, living in the midst of a renovation,
is NOT a pleasant experience. So what does it take get the macrophages to leave ? Well
you might think, they will just simply pack up their bags and leave, when the job is done.
It turns out, they don’t spontaneously MOVE ON. They have to be TOLD to leave. There are
quite a few chemicals, that do this. Collectively they are referred to as the SPMs or specialized
pro-resolving mediators, there are half a dozen of them, their names are not so important.
For the geeks, they include resolvins, protectins, maresins, lipoxins, annexins. What is important
for you to know, is that many of them, are chopped up bits of omega-3 fatty acids. Fat
cells are capable of chopping up the omega 3 fatty acids. But is seems in inflamed fat
cells, this process is not running smoothly. Now there are probably multiple reasons for
this dysregulation – most of which YOU can do very little about. But there is one thing,
you can do, to help improve the levels of SPMs, in your fat cells. Numerous studies
suggest SPM levels, are correlated with intake of omega-3 fatty acids. The more omega-3 fatty
acids you eat, the more omega-3s will be found in fat cell membranes. And with more there,
when the chopping up happens……… more SPMs will be formed – improving the inflammatory
resolving capacity. Helping you dial down the unremitting inflammation and restoring
metabolic balance. Unfortunately metabolic dysregulation is a vicious cycle. Consuming
more omega-3 fatty acids (think fish) and consuming less omega-6 fatty acids (think
vegetable oils) in your diet, is one step you can take to “correct” the metabolic
imbalance. Note, when you can, opt for natural sources of omega-3 fatty acids, rather than
supplements. Unfortunately a lot of the time, the fatty acids in supplements are a little
“damaged” , they’ve been oxidized, and in this state, they create TROUBLE, not SPMS.
Which is your goal. More specialized pro-resolving mediators will help you create BETTER BODY
CHEMISTRY and BETTER HEALTH. Interested in discovering more ways to create BETTER BODY
CHEMISTRY or need a little help getting your body chemistry on track ? Visit our website
at www better body chemistry dot com, browse our library or enrol in one of our courses
or programmes. The advice is simple to follow and based on real science, not hype. Know
someone whose fat cells are creating LOW GRADE INFLAMMATION ? Share this video with them
– so they know how help there fat cells send the fat remodelling team home, when the
job is done. And if this is your first time here, be sure to subscribe to our channel,
so you catch future episodes of BETTER BODY CHEMISTRY TV. Thank you so much for watching
and I’ll see you next time. Remember small things can make a big difference to your health.