Reduce Hunger Pains During Intermittent Fasting! [WHAT TO DRINK] · Dr. Jason Fung Clip

September 29, 2019 0 By Ewald Bahringer

– [Narrator] Welcome to the HVMN podcast. What we do with our bodies today becomes the foundation
of who we are tomorrow. This is Health Via Modern Nutrition. – A lot of people in
our groups always ask, “Oh, should I drink bone
broth, MCT oils, coconut oils, green tea, coffee?” I think your point
around bone broth perhaps not being ideal for triggering autophagy because it is amino acids, and amino acid triggers mTORC
which is what hypothesized to control or mediates autophagy – For like diabetes, it’d
be perfectly acceptable because that little bit of amino acid is not gonna do anything to you. It’s not gonna, it’s gonna
have so little effect and same for a lot of people
ask about bulletproof coffee and MCT oils again, so you’ve got calories but you’ve got very little insulin effect. So, again, if your point is to
try and lower insulin effect for weight loss or
diabetes, hey, that’s great, then you are going to be able
to take the bulletproof coffee or MCT oil and still get
the lowering of insulin that you want. So, keeping your goals in mind, you say, “Okay, well, that’d be perfectly
fine for type 2 diabetes. Bone broth, and typically
we’ll use bone broth for more longer fast, 36 hours plus. Green tea is a very interesting substance and I’ve been talking
a bit more about that lately because it’s one of the things that has, traditionally, if you look at traditional
Chinese medicine it’s actually one of the
substances that has been always purportedly helpful for weight loss. And if you look at the studies, what’s interesting is a couple of things one is that green tea typically
has much higher levels of the catechins, so the catechins are the
antioxidants and the flavanols the compound that’s
thought to be responsible for the benefits, but
they’re at much high doeses they’re at like ten cups a day sort of, level which most people don’t get to. But that’s what the studies are at, and it shows you can lose
about an extra kilogram of weight, with that what the
catechins do is they block and enzyme called COMT. And COMT is responsible for
breaking down your adrenalin, so if you block the COMT
our adrenalin goes up. So what happens is that you
get this activation of the sympathetic nervous system
and your energy expenditure can go up by about 4%. So not a huge increase, but significant. Essentially when your losing
weight a lot of the problems come when your metabolic
rate is going down. So if you can take the
green tea catechins, and increase your metabolic
rate, that’s huge. The other thing that
they showed in this study from just like 2016 is a
randomized controlled trial, is that when you compare it to placebo you get a reduction in Ghrelin. So Ghrelin is a hunger hormone
and if you lower Ghrelin you have less hunger which is
exactly what people tell us. – Green tea catechins, interesting. – The green tea catechins, yeah absolutely and it’s very interesting so
it’s like that’s great because the main problem with weight loss, is that you have too much hunger and your metabolic rate is
slowing, that’s why people fail with weight loss. Now you have an all natural substance that people have been using
for thousands of years, that increases your metabolic
rate and lowers your hunger, and what people tell us all
the time they drink green tea and then there hunger sorta goes away. – I was gonna ask
caffeine’s also known to be an appetite suppressant, were they going for that – Yeah it’s an additive effect,
in fact when you compare catechins and caffiene or caffeine alone, you get better effect with
the catechins plus caffiene. So it seems that they – (narrator) there you go – Actually have a better affect. So what caffiene does is it
blocks this other enzyme called phosphodiesterase which
also raises our adrenaline, so they actually work
through different pathways and of course, normal green tea has both catechins and caffeine. You can decaffeinate it but
I don’t recommend it because if you want the benefit
you gotta have both of them to get you know, twice the benefit. So I was just saying,
it’s interesting that some of the studies they show that Asians actually get a better weight
loss affect than Caucasians, because you get an average
weight loss of 1.5 kg for Asians vs 0.8 kg for Caucasians
and the reason is that, Asians have a higher incidents
of this high activity COMT so that’s the enzyme that’s
being blocked by green tea, so if your Asian and you have
a lot of activity of the COMT blocking it is gonna
give you a better affect. So it’s like okay that’s
really fascinating, but nevertheless 0.8 kg is
still a pretty good affect even for Caucasians. But it may even be better for
Asians which is huge because you look at the obesity epidemic
and like China and stuff it’s like massive, because the
numbers are huge over there. – (narrator) Right. – The problem is that the dose
of catechins you have to have is very high, you have to
have up to like 10 cups a day which isn’t feasible for most people and that’s where we worked with PTea. So what’s interesting about PTea, first their tea is really
great, I love the stuff. What they’ve done is they cold brew it and then they sort of
dehydrate it, so it’s basically crystals of concentrated tea. That’s all it is, it’s a
whole food it’s not like what they do in the
studies which is kind of industrially extract
the catechins and then add it to the green tea. This is sort of a just
concentrated cold brew tea, that’s all it is. We have people to help
with all kinds of stuff, but then when your fasting
it’s like oh yeah your like, outta luck, like just
do it man just man up and it’s like okay well you
don’t do that for anybody else we create stuff to help
them, so because nothing was available we’ve created this. I mean bulletproof coffee
is sort of a similar idea but it’s different I mean that’s people use as
a sort of fasting aid as well they don’t always say that
but that’s essentially what they’re doing. – It’s basically what they’re doing, I think the kinda of funny
thing with bulletproof coffee is that you’re eating like
far to many calories of fat so it’s just that, you’re
getting a alot of calories so I think, at a certain
point it’s still like you’re eating a lot of calories, and it’s hard to lose weight if you’re just eating like 3,000 of butter. So I like the tea , cause
again it’s like very a caloric if there’s not many calories. One thing that we saw that’s
interesting from a ketone asset perspective one of our
projects was a paper published actually kind of near
your back thereat UBC and the University of
Columbia showing that acute use of ketone actually
reduces a glycaemic response so what that means is that
a keto nester vs plecebo before a sugar test or a
glucose tolerance test, which is kind of a standard
test for insulin reserves for insulin reserves
resistance or sensitivity reduce the glyaecymic
response I’m curios… – I think exogenous ketones
have a role to play, and this kind of goes along
with this sort of fasting aids and sorta thing, because it’s not quite
a whole food obviously but again it’s something
that may help along the way so there’s a couple of things, one is that the sort of
properties of ketones have not been well appreciated for a long time. I don’t think anybody
really looks at it ever. So but lately with this
sorta interest in this ketogenic diet, you’re getting these really really interesting
thing’s popping up like oh hey you can treat
seizures with is, oh hey you can enhance athletic
performance with it, oh hey if you get fat adapted
hey endurance athletics maybe particularly beneficial if your running your body off ketones. And there point is that if
you take a ketone supplement you can get your ketone levels
much higher much faster. So the fastest natural
way to do it is fasting, but if you take a ketone faster
your gonna get way higher. You know like, right away almost. So is there some benefit to that, and increasingly a lot of
evidence says yes there could be some potential benefits. The ketogenic diet was
originally described like hundreds like 100 years ago
as a treatment for seizures and then it got lost with the
development of medications and it took not a doctor, but a film producer or you know this is the story
of the charlie foundation the son of a famous Hollywood producer had intractable seizures, nothing worked, none of the meds worked, he had the best you know doctors and it took
him, researching the archives to find that this ketogenic
diet would reduced seizures, so he tried it on his son and boom. All his seizures went
away and it’s like okay that’s a great story, why were the doctors
not the ones to do this because they knew about it 100 years ago, and then they totally forgot about it and it’s like it takes
a Hollywood producer to tell you how to do your
job? Like are you kidding me and I always think that
that’s very instructive because a lot of these things
get met with skepticism by the sort of doctors sort of mainstream medicine professionals, but
it’s like when it works it works then your job is to
understand why it works. Ketones falls into that range where maybe there’s some benefits to doing it but if it works, don’t
just say oh that’s quackery because that’s what everybody says oh I mean I got my fair share of that oh fasting that’s just quakery,
now it’s like oh you know – (narrator) they’ve all
learned about it now. (laughing) yeah there like of course it works you’re not eating so your
blood sugars will go down and it’s like, that’s not
what you said four years ago five years ago you said
” that’ll never work, you’re a quack” like but if you don’t eat
you’ll lose weight, their like no you won’t like how are
you not gonna lose weight. This is the same thing
with ketones so that we see in that study what you see
is that there’s a benefit to the ketones in terms of
reducing the blood glucose and of course this is one
of the areas that I’m very sort of passionate about,
which is type 2 diabetes and hey is there a benefit there? So it’s very preliminary
obviously but maybe you can use it as an adjunct in some way, maybe you can use it in
conjunction with the ketogenic diet or conjunction with fasting
or some of these dietary mechanisms or even with your
regular medications and maybe you can lower the blood
glucose and is there benefit so maybe the answer is yes, we don’t know. All we can say is that
it’s worthwhile studying. The other thing I think is very
interesting about exogenous ketones in type 2 diabetics anyway, is that you can measure this
ketone to a glucose index so as your blood glucose
falls your ketone should rise because your body is essentially
switching over from burning to burning ketones and burning fat. This doesn’t always happen
in type 2 diabetics. So if your glucose falls,
your ketones don’t rise – So you feel like (bleep) – Yeah exactly (laughing) so you got no glucose, you
got no ketones your just feeling like crap. Now if you stick it out
long enough your body will eventually produce ketones
because it’s not gonna die, but in the meantime it’s
not as easy as it could be and we’ve studied this, we
know that this sorta of glucose ketone index exists and that
there are different slopes for different people, so
normal people glucose down, ketones up, type 2 diabetics,
a lot of them, glucose down ketones not up, so what do you do? Well that’s where exogenous
ketones could have a benefit maybe if you define the
proper place to use it you could say okay we’ll give them ketones until they get into that
ketonic state themselves – Until obviously they produce it – Exactly because they
can’t endogenously produce. So if you’re trying to get
into that ketonic state, but your falling into
this low energy state where you have no glucose,
no ketones you can bridge it with exogenous ketones until
that fasting kinda kicks in and you produce endogenous ketones. It’s like hey that’d be a great solution, then you can get into there,
then you can start getting better from the diabetes and stuff. – (narrator) Yeah. – So many possibilities here, and I think that paper
was a great first step – Yeah no I appreciate
your perspective there as someone who’s looked
at it clinically across.